The Team Sky rider is set to become the first Briton to take home the yellow jersey after he finished the individual stage with a lead of three minutes, 21 seconds.
Today's time trial was a race against the clock and took riders over 33 miles (53.5km) from Bonneval to Chartres.
Wiggins punched the air as he crossed the finish line in one hour, four minutes, 13 seconds, for his second stage win of this Tour.
His Team Sky colleague Christopher Froome was second - 1:16 behind. Luis Leon Sanchez of Spain was third, 1:50 back.
Sunday's stage is traditionally a ceremonial ride onto the Champs-Elysees for the finale of the three-week race and as a result, Wiggins will lead the peloton through the streets of Paris.
Earlier, the British champ was given a good luck message from one of his boyhood idols - Paul Weller.
The former frontman of The Jam, also known as 'the Modfather' by fans, sent Wiggins a personal message ahead of the 33-mile race against the watch.
"I want to wish Bradley luck for the finale of the Tour de France," he said.
"It is great he's doing so well and it shows the years of hard work pay off. Good luck mate."
Wiggins successfully negotiated the penultimate road stage by playing a key role in team mate Mark Cavendish's win on the 132-mile route from Blagnac to Brive-la-Gaillarde.
Afterwards, the 32-year-old triple Olympic champion travelled north to the Team Sky hotel in Chartres in luxury, by helicopter.
Wiggins is grateful for all the messages of support he has received so far.
"It's been humbling really. I'm just a fan of the sport. It's nice that something like this can inspire so many people," he said.